Publications

Botha, J., Handberg, A., Simonsen, J.B. Lipid-based strategies used to identify extracellular vesicles in flow cytometry can be confounded by lipoproteins: Evaluations of annexin V, lactadherin, and detergent lysis (2022) Journal of Extracellular Vesicles, 11 (4), art. no. e12200, .

Lättekivi, F., Guljavina,I., Midekessa, G., Viil, J., Heath, P.R., Bæk, R., Jørgensen, M.M., Andronowska, A., Kingo, K., Fazeli, A., (2022) “Profiling blood serum extracellular vesicles in plaque psoriasis and psoriatic arthritis patients reveals potential disease biomarkers”; J. Mol. Sci. 23 (7) 4005; https://doi.org/10.3390/ijms23074005

Gu, T., Just, J., Stenz, K.T., Yan, Y., Sieljack, P., Wang, J., Groennebaek, T.S., Jakobsgaard, J.E., Rindom, E., Herskind, J., Gravholt, A., Lassen, T.R., Jørgensen, M., Bæk., R., Gutiérre-Jiménez, E., Iversen, N.K., Rasmussen, P.M., Nyengaard, J.R., Jørgensen, M.M., de Paoli, F., Bøtker, H.E., Kjems, J., Vissing, K., Drasbek, K.R., (2022) The Role of Plasma Extracellular Vesicles in Remote Ischemic Conditioning and Exercise-Induced Iscemic Tolerance. Int. J. Mol. Sci., 23, 3334. IF 4.5.

Akbar N., Britwaite, A.T., Corr, E.M., Koelwyn, G.J., van Solingen, C., Cochain,C., Saliba, A.-E., Corbin, A., Pezzolla, D., Jørgensen, M.M., Bæk, R., Edgar, L., Villiers, C.D., Gunadasa-Rohling, M., Banerjee, A., Paget, D., Lee, C., Hogg, E., Costin, A., Dhaliwal, R., Johnson, E., Krausgruber, T., Riepsaame, J., Melling, G.E., Shanmuganathan, M., Bock, C., Carter, D.R.F., Channon, K.M., Riley, P.R., Udalova, I.A., Moore, K.J., Anthony, D., Choudhury, R.P. (2022) “Rapid neutrophil mobilization by VCAM-1+endothelial cell-derived extracellular vesicles”., Cardiovascular Research, Epub a head of print https://doi.org/10.1093/cvr/cvac012. IF10.7

Jørgensen, M. M, Sloth, J.K., Bæk, R., (2021) “Optimization of High-Throughput Multiplexed Phenotyping of Extracellular Vesicles Performed in 96-well microtiter plates”, Polymers, 13(14), 2368. IF4.32

Nielsen, J.E., Honoré, B., Vestergård, K., Maltesen, R.G., Christiansen, G., Bøge, A.U., Kristensen, S.R., Pedersen, S. Shotgun-based proteomics of extracellular vesicles in Alzheimer’s disease reveals biomarkers involved in immunological and coagulation pathways (2021) Scientific Reports, 11 (1), art. no. 18518,

Rasmussen, R.W., Botha, J., Prip, F., Sanden, M., Nielsen, M.H., Handberg, A. Zoom in on antibody aggregates: A potential pitfall in the search of rare ev populations (2021) Biomedicines, 9 (2), art. no. 206, pp. 1-17.

Rajaratnam, N., Ditlevsen, N.E., Sloth, J.K., Bæk, R., Jørgensen, M.M., Christiansen, O.B. (2021) “Extracellular Vesicles: An important biomarker in recurrent pregnancy loss”, J Clin Med., 10, 2549. IF 3.3.

Pedersen, S., Kristensen, A.F., Falkmer, U., Christiansen, G., Kristensen, S.R. Increased activity of procoagulant factors in patients with small cell lung cancer (2021) PLoS ONE, 16 (July), art. no. e0253613,

Lassen, T. R., Just, J., Hjortbak, M., Jesprsen, N., Stenz, K., Gu, T., Yan, Y., Su, J., Hansen, J., Bæk, R., Jørgensen, M.M., Nyengaard, J., Kristiansen, S., Drasbek, K., Kjems, J., Bøtker, H., (2021) “Cardioprotection by remote ischemic conditioning is transferable by plasma and mediated by extracellular vesicles”, Basic Research of Cardiology.116:11, JIF 11.9.

Botha, J., Pugsley, H.R., Handberg, A. Conventional, high-resolution and imaging flow cytometry: Benchmarking performance in characterisation of extracellular vesicles (2021) Biomedicines, 9 (2), art. no. 124, pp. 1-24

Jørgensen, M. M., Bæk., R., Sloth, J., Varming, K., Christiansen, O., Ditlevsen, N., Rajaratnam, N., (2020) Treatment with intravenous immunoglobulin increases the level of small EVs in plasma of pregnant women with recurrent pregnancy loss. J Reprod. Imm. 140, 103128. JIF 4.0

Askeland, A., Borup, A., Østergaard, O., Olsen, J.V., Lund, S.M., Christiansen, G., Kristensen, S.R., Heegaard, N.H.H., Pedersen, S. Mass-spectrometry based proteome comparison of extracellular vesicle isolation methods: Comparison of ME-kit, size-exclusion chromatography, and high-speed centrifugation (2020) Biomedicines, 8 (8), art. no. 246,

Nielsen, J.E., Pedersen, K.S., Vestergård, K., Maltesen, R.G., Christiansen, G., Lundbye-Christensen, S., Moos, T., Kristensen, S.R., Pedersen, S. Novel blood-derived extracellular vesicle-based biomarkers in alzheimer's disease identified by proximity extension assay (2020) Biomedicines, 8 (8), art. no. 199,

Schou, A.S., Nielsen, J.E., Askeland, A., Jørgensen, M.M., (2020) Extracellular vesicles-associated proteins as potential biomarkers. Advances in Clinical Chemistry, Vol 99. IF 3.3

Just, J., Yan, Y., Farup, J., Sieljacks, P., Sloth, M., Venø, M., Gu, T., Vincenzo de Paoli, F., Nyengaard, J.R., Bæk, R., Jørgensen, M.M., Kjems, J., Vissing, K., Drasbek, K.R., (2020) Blood flow-restricted resistance exercise alters the surface profile, miRNA cargo and functional impact of circulating extracellular vesicles. Scientific Report, SREP-19-33767 JIF 3.9

Dissanayake, K., Nömm, M., Lättekivi, F., Ressaissi, Y., Godakumara, K., Lavrits, A., Midekessa, G., Viil, J., Bæk, R., Jørgensen, M.M., Bhattacharjee, S., Andronowska, A., Salumets, A., Jaakma, Ü., Fazeli, A., (2020) Individually cultured bovine embryos produce extracellular vesicles that have the potential to be used as non-invasive embryo quality markers, Theriogenology, 149:104-116. JIF 2.1

Jung, A. L., Jørgensen, M.,M., Bæk, R., Griss, K., Han, M., auf dem Brinke, K., Timmesfeld, N., Bertrams, W., Greulich, T., Koczulla, R., Hippenstiel, S., Suttorp, N., Schmeck, B., (2019) Surface Proteome of plasma extracellular vesicles as biomarkers for pneumonia and acute exacerbation of chronic obstructive pulmonary disease. J. Infectious Diseases, JIF 5.0

Nielsen, T., Kristensen, S.R., Gregersen, H., Teodorescu, E.M., Christiansen, G., Pedersen, S. Extracellular vesicle-associated procoagulant phospholipid and tissue factor activity in multiple myeloma (2019) PLoS ONE, 14 (1), art. no. e0210835,

Bhargava, P., Nogueras-Ortiz, C., Chawla, S., Bæk, R., Jørgensen, M. M., Kapogiannis, D., (2019) Altered Levels of Toll-like Receptors in Circulating Extracellular Vesicles in Multiple Sclerosis. Cells, 8, 1058. JIF 4.3

Gudbergsson, J. M., Kostrikov, S., Johnsen, K. B., Fliedner, F. P., Stolberg, C. B., Humle, N., Hansen, A. E., Kristensen, B. W., Christiansen, G., Kjær, A., Andresen, T. L. & Duroux, M., (2019) "A tumorsphere model of glioblastoma multiforme with intratumoral heterogeneity for quantitative analysis of cellular migration and drug response", In : Experimental Cell Research. 379, 1, p. 73-82 10 p.

Brahmer, A., Neuberger, E., Esch-Heisser, L., Haller, N., Jørgensen, M.M., Bæk, R., Möbius, W., Simon, P., Krämer-Albrs, E.-M. (2019) Platelets, endothelial cells and leukocytes contribute to the exercise-triggered release of extracellular vesicles into the circulation. J Extracellular. Vesicles.,vol 8., 1615820. JIF 14.9

Nielsen, M.H., Sabaratnam, R., Pedersen, A.J.T., Højlund, K., Handberg, A. Acute Exercise Increases Plasma Levels of Muscle-Derived Microvesicles Carrying Fatty Acid Transport Proteins (2019) Journal of Clinical Endocrinology and Metabolism, 104 (10), pp. 4804-4814.

Garcia, N.A., González-King, H., Grueso, E., Sánchez, R., Martinez-Romero, A., Jávega, B., O'Connor, J.E., Simons, P.J., Handberg, A., Sepúlveda, P. Circulating exosomes deliver free fatty acids from the bloodstream to cardiac cells: Possible role of CD36 (2019) PLoS ONE, 14 (5), art. no. e0217546, .

Mørk, M.,, Andreasen, J.J., Rasmussen, L.H., Pedersen, S., Bæk, R., Jørgensen, M.M.,, G., Kristensen, S.R., (2019) Elevated blood plasma levels of tissue factor-bearing extracellular vesicles in patients with atrial fibrillation. Thrombosis Research, vol 173, 141-150. IF 2.8

Théry, C., et al. (2018) Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines. J Extracell. Vesicles. Vol 7, 2018.

Kristensen SR, Botha J, Handberg A. Blu-ray beyond music and movies—novel approach to diagnostics measuring specific extracellular vesicles. J Lab Precis Med 2018;3:84.

Mørk, M., Nielsen, M.H., Bæk, R., Jørgensen, M.M., Pedersen, S., Kristensen, S.R., (2018) Postprandial Increase in Blood Plasma Levels of Tissue Factor–Bearing (and Other) Microvesicles Measured by Flow Cytometry: Fact or Artifact?TH Open 2 (02), e147-e157

Botha J, Nielsen MH, Christensen MH, Vestergaard H, Handberg A. Bariatric surgery reduces CD36-bearing microvesicles of endothelial and monocyte origin. Nutr Metab (Lond) 2018;15:76.

Sanden M, Botha J, Nielsen MRS, Nielsen MH, Schmidt EB, Handberg A. BLTR1 and CD36 Expressing Microvesicles in Atherosclerotic Patients and Healthy Individuals. Front Cardiovasc Med 2018 Oct 30;5:156.

Nielsen, T., Kristensen, A.F., Pedersen, S., Christiansen, G., Kristensen, S.R., (2018) Investigation of procoagulant activity in extracellular vesicles isolated by differential ultracentrifugation. J Extracellular Vesicles, Vol 8, 1454777

Vinterhøj, HSH., Stensballe, A., Duroux, M., Gazerani, P.,(2018) "Characterization of rat primary trigeminal satellite glial cells and associated extracellular vesicles under normal and inflammatory conditions" J Proteomics, S1874-3919(18)30108-8

Johnsen, K.B., Gudbergsson, J.M., Duroux, M., Moos, T., Andresen, T.L., Simonsen, J.B., (2018) On the use of liposome controls in studies investigating the clinical potential of extracellular vesicle-based drug delivery systems - A commentary, J Controlled Release, 269, 10-14.

Soares, R.P., et al., (2017) Highlights of the São Paulo ISEV workshop on extracellular vesicles in cross-kingdom communication. J Extracellular Vesicles, 6, 1, 1407213.

Revenfeld, A.L.S., Bæk, R., Jørgensen, M.M., Varming, K., Stensballe, A. (2017) Induction of a Regulatory Phenotype in CD3+ CD4+ HLA-DR+ T Cells after Allogeneic Mixed Lymphocyte Culture; Indications of Both Contact-Dependent and -Independent Activation, Int. J. Mol. Sci. 2017, 18(7), 1603; doi:10.3390/ijms18071603

Botha, J., Magnussen, L.V., Nielsen, M.H., et al., (2017) “Microvesicles Correlated with Components of Metabolic Syndrome in Men with Type 2 Diabetes Mellitus and Lowered Testosterone Levels But Were Unaltered by Testosterone Therapy,” Journal of Diabetes Research, vol. 2017, Article ID 4257875. doi:10.1155/2017/4257875

Eitan, E., Green, J., Bodogai, M., Mode, N.A., Bæk, R., Jørgensen, M.M., Freeman, D.W., Witwer, K.W., Zonderman, A.B., Biragyn, A., Mattson, M.P., Hooten, N.N., and Evans, M.K., (2017) “Age-Related Changes in Plasma Extracellular Vesicle Characteristics and Internalization by Leukocytes.” Nature, Scientific Reports.