Publications

Publications

Revenfeld, A.L.S., Bæk, R., Jørgensen, M.M., Varming, K., Stensballe, A. (2017) Induction of a Regulatory Phenotype in CD3+ CD4+ HLA-DR+ T Cells after Allogeneic Mixed Lymphocyte Culture; Indications of Both Contact-Dependent and -Independent Activation, Int. J. Mol. Sci. 2017, 18(7), 1603; doi:10.3390/ijms18071603

Botha, J., Magnussen, L.V., Nielsen, M.H., et al., (2017) “Microvesicles Correlated with Components of Metabolic Syndrome in Men with Type 2 Diabetes Mellitus and Lowered Testosterone Levels But Were Unaltered by Testosterone Therapy,” Journal of Diabetes Research, vol. 2017, Article ID 4257875. doi:10.1155/2017/4257875

Eitan, E., Green, J., Bodogai, M., Mode, N.A., Bæk, R., Jørgensen, M.M., Freeman, D.W., Witwer, K.W., Zonderman, A.B., Biragyn, A., Mattson, M.P., Hooten, N.N., and Evans, M.K., (2017) “Age-Related Changes in Plasma Extracellular Vesicle Characteristics and Internalization by Leukocytes.” Nature, Scientific Reports.

Mørk, M., Handberg, A., Pedersen, S., Jørgensen, M.M., Bæk, R., Nielsen, M.K., and Kristensen, S.R., (2017) "Prospects and limitations of antibody-mediated clearing of lipoproteins from blood plasma prior to nanoparticle tracking analysis of extracellular

vesicles." J. Extracellular Vesicles, Vol 6, 1308779.

Bæk, R., Jørgensen, M.M. (2017) Multiplexed phenotyping of small extracellular vesicles using protein microarray (EV Array). "Exosomes and Microvesicles: Methods and Protocols", Methods in Molecular Biology, vol. 1545.

Sandfeld-Paulsen B., Aggerholm-Pedersen N., Bæk R., Jakobsen K.R., Meldgaard P., Folkersen B.H., Rasmussen T.R., Varming K., Jørgensen M.M., Sorensen B.S. (2016) Exosomal proteins as prognostic biomarkers in non-small cell lung cancer. Mol. Onco Epub ahead of print.

Vogel, R., Coumans, F.A.W., Maltesen, R.G., et al., (2016) A standardized method to determine the concentration of extracellular vesicles using tunable resistive pulse sensing. J Extracell Vesicles, 5.

Sandfeld-Paulsen B., Jakobsen K.R., Bæk R., Folkersen B.H., Rasmussen T.R., Meldgaard P., Varming K., Jørgensen M.M., Sorensen B.S. (2016) Exosomal Proteins as Diagnostic Biomarkers in Lung Cancer. J Thorac Oncol. 11, 10, 1701-10.

Bæk, R., Søndergaard, E.K.L., Varming, K.,Jørgensen, M.M., (2016) The impact of various preanalytical treatments on the phenotype of small extracellular vesicles in blood analyzed by protein microarray. J. Immunol. Meth. Epub

Bæk, R., Varming, K.,Jørgensen, M.M., (2016) Does smoking, age or gender affect the protein phenotype of extracellular vesicles in plasma?. Transf. Apheresis Sci., Aug. 2016.

Jørgensen, M.M., Bæk, R., Tveito, S., Schmeck, B., Greulich, T., Stensballe, A., Varming, K., (2016) Phenotyping of Small Extracellular Vesicles from Clinically Important Body Fluids using Protein Microarray. Book Chapter in “Exosomes: Biogenesis, Therapeutic Applications and Emerging Research”, edited by Arlando Meyers, Nova Publishers.

Mork M, Pedersen S, Botha J, Lund SM, Kristensen SR. (2016) Preanalytical, analytical, and biological variation of blood plasma submicron particle levels measured with nanoparticle tracking analysis and tunable resistive pulse sensing. Scand J Clin Lab Invest 19:1-12.

Riis, S., Stensballe, A., Emmersen, J., Pennisi, C.P., Birkelund, S., Zachar, V.,

and Fink, T., (2016) Mass spectrometry analysis of adipose-derived stem cells reveals a significant effect of hypoxia on pathways regulating extracellular matrix. Stem Cell Research and Therapy 7(1), 52.

Pugholm, L.H., Bæk, R., Søndergaard, E.K.L., Revenfeld, A.L.S., Jørgensen M.M., Varming, K., (2016) Phenotyping of leukocytes and leukocyte-derived extracellular vesicles. J. Imm. Res. Volume 2016 (2016), Article ID 6391264, 12 pages.

Revenfeld, A.L.S., Søndergaard, E.K.L., Stensballe, A., Bæk, R., Jørgensen, M.M., Varming, K., (2016) Characterization of a Cell-culturing System for the Study of Contact-independent Extracellular Vesicle Communication. J. Circ. Biomark., 5, 3.

Johnsen, K.B., Gudbergsson, J.M., Skov, M.N., Christiansen, G., Gurevich, L.,

Moos, T., Duroux, M., (2016) Evaluation of electroporation-induced adverse effects

on adipose-derived stem cell exosomes, Cytotechnology.

Nielsen MH, Irvine H, Vedel S, Raungaard B, Beck-Nielsen H, Handberg A.(2016) The impact of lipoprotein-associated oxidative stress on cell-specific microvesicle release in patients with familial hypercholesterolemia. Oxidative Medicine and Cellular Longevity. Article ID 2492858

Lener, T., Gimona, M., et al., (2016) Applying extracellular vesicles based therapeutics in clinical trials - an ISEV position paper. J Extracell Vesicles, 5.

Søndergaard, E.K.L., Pugholm, L.H., Bæk, R., Jørgensen, M.M., Revenfeld, A.L.S., Varming, K., (2016) Oxygen-related Differences in Cellular and Vesicular Phenotypes Observed for Ovarian Cancer Cell Lines. J. Circ. Biomark. 5,1.

Andersen, H.H., Duroux, M.,Gazerani, P., (2015) Serum microRNA signatures in migraineurs during attacks and in pain-free periods. Molecular Neurobiology.

Gudbergsson, J.M., Johnsen, K.B., Skov, M.N., Duroux, M., (2015) Systematic review of factors influencing extracellular vesicle yield from cell cultures. Cytotechnology. i

Pugholm, L.H., Revenfeld, A.L.S., Søndergaard, E.K.L., Jørgensen, M.M. (2015) Antibody-based Assays for phenotyping of extracellular vesicles. BioMed Research International., vol 2015, ID524817, 15 pages.

Nielsen, TB, Nielsen, MH, Handberg A., (2015) :In vitro Incubation of Platelets with oxLDL Does Not Induce Microvesicle Release When Measured by Sensitive Flow Cytometry. Frontiers in Cardiovascular Medicine Vol. 2, 37.

Hjuler Nielsen, M., Irvine, H., Vedel, S., Beck-Nielsen, H., Handberg, A.,(2015).Elevated Atherosclerosis-Related Gene Expression, Monocyte Activation and Microparticle-Release Are Related to Increased Lipoprotein-Associated Oxidative Stress in Familial Hypercholesterolemia. / PloS one Vol. 10, Nr. 4, e0121516, 16.04.2015.

Jørgensen, M.M., Bæk, R., Varming, K., (2015) Potentials and Capabilities of the Extracellular Vesicle (EV) Array. J Extracell Vesicles, 4.

Jakobsen, K.R., Paulsen, B.S., Bæk, R., Varming, K., Sorensen, B.S., Jørgensen, M.M., (2015) Exosomal Proteins as Potential Diagnostic Markers in Advanced Non-Small Cell Lung Carcinoma. J Extracell Vesicles ,4.

Kim DK, Lee J, Kim SR, Choi DS,…. Jørgensen, M., et al., (2015) EVpedia: A Community Web Portal for Extracellular Vesicles Research. Bioinformatics, 31 (6), 933-9.

Nielsen, M.H., Beck-Nielsen, H., Andersen, M. N., Handberg, A., (2014) A flow cytometric method for characterization of circulating cell-derived microparticles in plasma. / Journal of Extracellular Vesicles Vol. 3, doi: 10.3402/jev.v3.20795. eCollection 2014.

Revenfeld, A.L.S., Bæk, R., Nielsen, M.H., Stensballe, A., Varming, K., Jørgensen, M., (2014) Diagnostic and prognostic potential of extracellular vesicles present in peripheral blood. Clinical therapeutics. Invited review – Clinical Therapeutics 36 (6); 830-46.

Johnsen KB, Gudbergsson JM, Skov MN, Pilgaard L, Moos T, Duroux M., (2014) A comprehensive overview of exosomes as drug delivery vehicles - Endogenous nanocarriers for targeted cancer therapy. Biochim Biophys Acta, Apr 18. doi: 10.1016/j.bbcan.2014.04.005

Jørgensen, M., Bæk, R., Pedersen, S., Søndergaard, E., Kristensen, S. R., Varming K., (2013) Extracellular Vesicle (EV) Array: microarray capturing of exosomes and other extracellular vesicles for multiplexed phenotyping. J Extracell Vesicles (2).

Wilhelmsen, P., Kjær, J., Thomsen, K.L., Nielsen, C.T., Dige, A.K., Maniecki, M.B., Heegaard, N., Grønbæk, H., Dahlerup, J.F.,; Handberg, A. (2013). Elevated platelet expression of CD36 may contribute to increased risk of thrombo-embolism in active inflammatory bowel disease. / Archives of Physiology and Biochemistry, Vol. 119, Nr. 5, 17.07, s. 202-8.

Mathivanan et. Al (2012) Vesiclepedia: A compendium for extracellular vesicles with continuous community annotation” PLoS Biol. 2012;10 (12).

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